A reverse evidence of rotavirus vaccines impact

Martinón Torres, Federico; Aramburo Caragol, Ángela; Martinon Torres, Nazareth; Cebey López, Miriam; Seoane Pillado, María Teresa; Redondo Collazo, Lorenzo; Martinón Sánchez, José María
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URI: http://hdl.handle.net/20.500.11940/2030
PMID: 23836258
ISSN: 2164-5515
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Date issued
2013
Journal title
Human Vaccines & Immunotherapeutics 
Type of content
Artigo
MeSH
Child, Preschool | Female | Gastroenteritis | Hospitalization | Humans | Infant | Infant, Newborn | Male | Retrospective Studies | Rotavirus Infections | Rotavirus Vaccines | Safety-Based Drug Withdrawals | Spain/epidemiology | Vaccination | Vaccine effectiveness | gastroenteritis | hospitalization | rotavirus infections | rotavirus vaccines
Abstract
In 2010, and due to a quality problem identified in the vaccine manufacture, the rotavirus (RV) vaccination was withheld in Spain during 5 months. Our study aimed to evaluate the impact that this sudden cease had on rotavirus acute gastroenteritis (RAGE) hospitalizations. An increase in RAGE hospitalization was observed in parallel to the drop in vaccine coverage. Here, we report the first reverse evidence of rotavirus vaccine impact.