Genomic characterisation of respiratory syncytial virus: a novel system for whole genome sequencing and full-length G and F gene sequences

Iglesias-Caballero, M.; Camarero-Serrano, S.; Varona, S.; Mas, V.; Calvo, C.; García, M.L.; García Costa, Juan; Vázquez-Morón, S.; Monzón, S.; Campoy, A.; Cuesta, I.; Pozo, F.; Casas, I.
Thumbnail
Estatísticas
Estatísticas
Identificadores
Identificadores
Rexistro completo
Servizos
Servizos
RISMendeleyLinksolver
Visualización ou descarga de ficheiros
Visualización ou descarga de ficheiros
Data de publicación
2023
Título da revista
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Tipo de contido
Artigo
MeSH
Humans | Respiratory Syncytial Virus Infections | Viral Fusion Proteins | Respiratory Syncytial Virus Vaccines | Respiratory Syncytial Virus, Human | Genomics | Whole Genome Sequencing | Antibodies, Viral
Resumo
To advance our understanding of respiratory syncytial virus (RSV) impact through genomic surveillance, we describe two PCR-based sequencing systems, (i) RSVAB-WGS for generic whole-genome sequencing and (ii) RSVAB-GF, which targets major viral antigens, G and F, and is used as a complement for challenging cases with low viral load. These methods monitor RSV genetic diversity to inform molecular epidemiology, vaccine effectiveness and treatment strategies, contributing also to the standardisation of surveillance in a new era of vaccines.
Attribution 4.0 International (CC BY 4.0)
A non ser que se indique outra cousa, a licenza do ítem descríbese comoAttribution 4.0 International (CC BY 4.0)