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dc.contributor.authorRuibal Morell, Alvaro 
dc.contributor.authorAguiar Fernández, Pablo
dc.contributor.authorDel Río Garma, María del Carmen 
dc.contributor.authorMenendez P
dc.contributor.authorArias J.i
dc.contributor.authorHerranz Carnero, Michel 
dc.date.accessioned2017-06-07T07:08:57Z
dc.date.available2017-06-07T07:08:57Z
dc.date.issued2015
dc.identifier.issn2049-9450
dc.identifier.urihttp://hdl.handle.net/20.500.11940/3132
dc.description.abstractThis study was conducted to investigate the clinicopathological parameters in elderly women (aged >70 years) with infiltrating lobular carcinoma (ILC) of the breast and compare the results with those obtained from younger patients (aged 55-70 years). The study sample included a total of 46 women with ILCs, 10 aged >70 and 36 aged 55-70 years. The parameters analysed were tumor size, histological grade (HG), axillary lymph node involvement, distant metastasis and immunohistochemical expression of estrogen, progesterone and androgen receptors, Ki67, p53 and B cell lymphoma 2. Compared to women aged 55-70 years, ILCs in women aged >70 years were commonly of larger size (P=0.068) and were more frequently HG3 (P=0.024). There were no statistically significant differences in the other parameters analysed. Furthermore, we were unable to determine differences in cancer recurrence and mortality in the two patient subgroups during our follow-up. In conclusion, our preliminary results, based on the limited number of cases included in this study, indicate that i) ILCs in women aged >70 years tended to be larger compared to those in women aged 55-70 years and were more frequently of grade 3; and ii) there were no significant differences in terms of recurrence and mortality between the two patient subgroups during our follow-up.
dc.language.isoeng
dc.titleClinicopathological characteristics of infiltrating lobular breast carcinoma in elderly women: Preliminary results
dc.typeArtigoes
dc.authorsophosRuibal A
dc.authorsophosAguiar P
dc.authorsophosdel Rio M.d.c
dc.authorsophosMenendez P
dc.authorsophosArias J.i
dc.authorsophosHerranz M
dc.identifier.doi10.3892/mco.2015.625
dc.identifier.pmid26807244
dc.identifier.sophos17712
dc.issue.number6
dc.journal.titleMolecular and Clinical Oncology
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Ferrol::Xerencia da Área de Ferrol::Análise clínicos
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago - Complexo Hospitalario Universitario de Santiago::Medicina nuclear
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago::IDIS.- Instituto de investigaciones sanitarias de Santiago
dc.page.initial1337
dc.page.final1340
dc.rights.accessRightsopenAccess
dc.typesophosArtículo Original
dc.volume.number3


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