TY - JOUR AU - Carrato, A AU - Benavides, M AU - Massuti, B AU - Ferreiro-Monteagudo, R AU - Garcia Alfonso, P AU - Falco, E AU - Reboredo Lopez, Margarita AU - Cano, T AU - Gallego, J AU - Vieitez, J M AU - Layos, L AU - Salud, A AU - Polo, E AU - Dotor, E AU - Duran-Ogalla, G AU - Rodriguez-Garrote, M AU - Calvo, A AU - Grande, E AU - Aranda, E PY - 2019 SN - 1471-2407 UR - http://hdl.handle.net/20.500.11940/15934 AB - BACKGROUND: Treatment of frail patients with advanced colorectal cancer (CRC) is controversial. This pilot phase II trial aimed to assess the efficacy and safety of regorafenib when administered in first-line to frail patients with advanced CRC.... LA - eng KW - Middle Aged KW - Neoplasm Metastasis KW - Hypophosphatemia KW - Follow-Up Studies KW - Pyridines KW - Humans KW - Treatment Outcome KW - Pilot Projects KW - Asthenia KW - Aged KW - Hypertension KW - Colorectal Neoplasms KW - Phenylurea Compounds TI - First-line single-agent regorafenib in frail patients with metastatic colorectal cancer: a pilot phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) DO - 10.1186/s12885-019-5753-7 T2 - BMC CANCER KW - CHUAC VL - 19 ER -