TY - JOUR AU - Bearz, A. AU - Martini, J.-F. AU - Jassem, J. AU - Kim, S.-W. AU - Chang, G.-C. AU - Shaw, A.T. AU - Shepard, D.A. AU - Dall'O, E. AU - Polli, A. AU - Thurm, H. AU - Zalcman, G. AU - García Campelo, María del Rosario AU - Penkov, K. AU - Hayashi, H. AU - Solomon, B.J. PY - 2023 SN - 1556-1380 UR - http://hdl.handle.net/20.500.11940/21427 AB - Introduction: Lorlatinib, a third-generation ALK tyrosine kinase inhibitor, improved outcomes compared with crizotinib in patients with previously untreated ALK-positive advanced NSCLC in the phase 3 CROWN study. Here, we investigated response... LA - eng KW - Humans KW - Crizotinib KW - Lung Neoplasms KW - Antineoplastic Agents KW - Anaplastic Lymphoma Kinase KW - Carcinoma, Non-Small-Cell Lung KW - Lactams, Macrocyclic KW - Protein Kinase Inhibitors KW - Mutation KW - Tumor Suppressor Protein p53 TI - Efficacy of Lorlatinib in Treatment-Naive Patients With ALK-Positive Advanced NSCLC in Relation to EML4::ALK Variant Type and ALK With or Without TP53 Mutations DO - 10.1016/j.jtho.2023.07.023 T2 - Journal of Thoracic Oncology M2 - 1581 KW - AS A Coruña KW - CHUAC VL - 18 ER -