TY  - JOUR 
AU  - Prieto-Díaz, R.
AU  - González-Gómez, M.
AU  - Fojo-Carballo, H.
AU  - Azuaje, J.
AU  - El Maatougui, A.
AU  - Majellaro, M.
AU  - Loza García, María Isabel
AU  - Brea Floriani, José Manuel
AU  - Fernández-Dueñas, V.
AU  - Paleo, M.R.
AU  - Díaz-Holguín, A.
AU  - Garcia-Pinel, B.
AU  - Mallo-Abreu, A.
AU  - Estévez, J.C.
AU  - Andújar-Arias, A.
AU  - García-Mera, X.
AU  - Gomez-Tourino, I.
AU  - Ciruela, F.
AU  - Salas, C.O.
AU  - Gutiérrez-De-Terán, H.
AU  - Sotelo, E.
PY  - 2023
SN  - 1520-4804
UR  - http://hdl.handle.net/20.500.11940/21478
AB  - The modulation of the A2Badenosine receptor is a promising strategy in cancer (immuno) therapy, with A2BAR antagonists emerging as immune checkpoint inhibitors. Herein, we report a systematic assessment of the impact of (di- and mono-)halogenation at...
LA  - eng
KW  - Cricetinae
KW  - Animals
KW  - Humans
KW  - Purinergic P1 Receptor Antagonists
KW  - CHO Cells
KW  - Halogenation
KW  - Leukocytes, Mononuclear
KW  - Adenosine A2 Receptor Antagonists
KW  - Receptor, Adenosine A2B
KW  - Ligands
KW  - Halogens
TI  - Exploring the Effect of Halogenation in a Series of Potent and Selective A2BAdenosine Receptor Antagonists
DO  - 10.1021/acs.jmedchem.2c01768
T2  - Journal of Medicinal Chemistry
M2  - 890
KW  - AS Santiago
KW  - IDIS
VL  - 66
ER  -