TY - JOUR AU - Luengo-Mateos, M. AU - González-Vila, A. AU - Vicente Dragano, N.R. AU - Ohinska, N. AU - Silveira-Loureiro, M. AU - González-Domínguez, M. AU - Estévez-Salguero, Á. AU - Novelle-Rodríguez, P. AU - López Pérez, Miguel A. AU - Barca-Mayo, O. PY - 2023 SN - 2211-1247 UR - http://hdl.handle.net/20.500.11940/21581 AB - Here, we demonstrate that hypothalamic astrocytic BMAL1 computes cyclic metabolic information to optimize energetic resources in a sexually dimorphic manner. Knockdown of BMAL1 in female astrocytes leads to negative energy balance and alters basal... LA - eng KW - Animals KW - Female KW - Male KW - Mice KW - Adipose Tissue, Brown KW - ARNTL Transcription Factors KW - Astrocytes KW - Diet, High-Fat KW - Energy Metabolism KW - Homeostasis KW - Hypothalamus KW - Obesity TI - Hypothalamic astrocytic-BMAL1 regulates energy homeostasis in a sex-dependent manner DO - 10.1016/j.celrep.2023.112949 T2 - Cell Reports KW - AS Santiago KW - IDIS VL - 42 ER -