TY - JOUR AU - Álvarez-Larrán, Alberto AU - Kerguelen, Ana AU - Hernández-Boluda, Juan Carlos AU - Pérez Encinas, Manuel Mateo AU - Ferrer-Marín, Francisca AU - Bárez, Abelardo AU - Martínez López, Joaquín AU - Cuevas, Beatriz AU - Mata, M. Isabel AU - García-Gutiérrez, Valentín AU - Aragües, Pilar AU - Montesdeoca, Sara AU - Burgaleta, Carmen AU - Caballero, Gonzalo AU - Hernández-Rivas, J. Ángel AU - Durán, M. Antonia AU - Gómez-Casares, María-Teresa AU - Besses, Carlos PY - 2016 UR - http://hdl.handle.net/20.500.11940/22503 AB - [EN] The clinical significance of resistance/intolerance to hydroxycarbamide (HC) was assessed in a series of 890 patients with polycythaemia vera (PV). Resistance/intolerance to HC was recorded in 137 patients (15·4%), consisting of: need for... LA - eng KW - Hydroxyurea KW - Prognosis KW - Drug Resistance KW - Drug Tolerance KW - Nucleic Acid Synthesis Inhibitors KW - Leukocyte Count KW - Treatment Outcome KW - Polycythemia Vera KW - Registries TI - Frequency and prognostic value of resistance/intolerance to hydroxycarbamide in 890 patients with polycythaemia vera DO - 10.1111/bjh.13886 T2 - British Journal of Haematology M2 - 786 KW - CHUS VL - 172 ER -