TY - JOUR AU - Jiang, Xuejuan AU - Esteban Castelao, J. AU - Vandenberg, David AU - Carracedo, Angel AU - Redondo, Carmen M. AU - Conti, David V. AU - Paredes Cotore, Jesus P. AU - Potter, John D. AU - Newcomb, Polly A. AU - Passarelli, Michael N. AU - Jenkins, Mark A. AU - Hopper, John L. AU - Gallinger, Steven AU - Le Marchand, Loic AU - Martinez, Maria E. AU - Ahnen, Dennis J. AU - Baron, John A. AU - Lindor, Noralane M. AU - Haile, Robert W. AU - Gago Dominguez, Manuela PY - 2013 SN - 1932-6203 UR - http://hdl.handle.net/20.500.11940/2305 AB - BACKGROUND: Recent genome-wide studies identified a risk locus for colorectal cancer at 18q21, which maps to the SMAD7 gene. Our objective was to confirm the association between SMAD7 SNPs and colorectal cancer risk in the multi-center Colon Cancer... LA - eng KW - Adult KW - Aged KW - Anti-Inflammatory Agents, Non-Steroidal KW - Body Mass Index KW - Case-Control Studies KW - Colonic Polyps KW - Colorectal Neoplasms KW - Female KW - Genetic Predisposition to Disease KW - Humans KW - Logistic Models KW - Middle Aged KW - Odds Ratio KW - Polymorphism, Single Nucleotide KW - Registries KW - Risk KW - Smad7 Protein KW - Smoking TI - Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry DO - 10.1371/journal.pone.0060464 T2 - PLoS One VL - 8 ER -