TY  - JOUR 
AU  - Diaz-Rodriguez, E.
AU  - Garcia-Rendueles, A. R.
AU  - Ibáñez-Costa, A.
AU  - Gutierrez-Pascual, E.
AU  - Garcia-Lavandeira, M
AU  - Leal, A.
AU  - Japon, M. A.
AU  - Soto, A.
AU  - Venegas, E.
AU  - Tinahones, F. J.
AU  - Garcia-Arnes, J. A.
AU  - Benito, P.
AU  - Angeles Galvez, M.
AU  - Jimenez-Reina, L.
AU  - Bernabeu Morón, Ignacio
AU  - Dieguez, C.
AU  - Luque, R.M
AU  - Castaño, J. P.
AU  - Alvarez, C. V.
PY  - 2014
SN  - 0013-7227
UR  - http://hdl.handle.net/20.500.11940/4567
AB  - Acromegaly is caused by somatotroph cell adenomas (somatotropinomas [ACROs]), which secrete GH. Human and rodent somatotroph cells express the RET receptor. In rodents, when normal somatotrophs are deprived of the RET ligand, GDNF (Glial Cell Derived...
LA  - eng
KW  - Adenoma
KW  - Apoptosis
KW  - Glial Cell Line-Derived Neurotrophic Factor
KW  - Growth Hormone-Secreting Pituitary Adenoma
KW  - Pituitary Neoplasms
TI  - Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF
DO  - 10.1210/en.2014-1034
T2  - Endocrinology
M2  - 4329
VL  - 155
ER  -