TY - JOUR AU - De Andrés González, Mª Carmen AU - Pérez Pampín, Eva AU - Calaza Cabanas, Manuel AU - Santaclara Nores, Francisco Javier AU - Ortea García, Ignacio AU - Gómez-Reino Carnota, Juan Jesús AU - González Martínez-Pedrayo, Antonio PY - 2015 SN - 1478-6354 UR - http://hdl.handle.net/20.500.11940/4788 AB - INTRODUCTION: DNA methylation is an epigenetic mechanism regulating gene expression that has been insufficiently studied in the blood of rheumatoid arthritis (RA) patients, as only T cells and total peripheral blood mononuclear cells (PBMCs) from... LA - eng KW - Adult KW - Aged KW - Antirheumatic Agents KW - Arthritis, Rheumatoid KW - B-Lymphocytes KW - Cell Cycle Proteins KW - Chromatography, High Pressure Liquid KW - DNA (Cytosine-5-)-Methyltransferase 1 KW - DNA (Cytosine-5-)-Methyltransferases KW - DNA Methylation KW - DNA-Binding Proteins KW - Dioxygenases KW - Female KW - Gene Expression Regulation KW - Humans KW - Leukocytes, Mononuclear KW - Male KW - Methotrexate KW - Middle Aged KW - Mixed Function Oxygenases KW - Nuclear Proteins KW - Proto-Oncogene Proteins KW - Reverse Transcriptase Polymerase Chain Reaction KW - Spectrometry, Mass, Electrospray Ionization KW - T-Lymphocytes KW - Time Factors TI - Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate DO - 10.1186/s13075-015-0748-5 T2 - ARTHRITIS RESEARCH & THERAPY M2 - 233 VL - 17 ER -