TY - JOUR AU - A.W., Dodd AU - Rodriguez-Fontenla, Cristina AU - M., Calaza AU - A., Carr AU - Gómez-Reino Carnota, Juan Jesús AU - A., Tsezou AU - L.N., Reynard AU - González Martínez-Pedrayo, Antonio AU - J., Loughlin PY - 2011 SN - 1063-4584 UR - http://hdl.handle.net/20.500.11940/5735 AB - OBJECTIVE: The common single nucleotide polymorphism (SNP) rs143383 in the 5' untranslated region (5'UTR) of growth and differentiation factor 5 (GDF5) is strongly associated with osteoarthritis (OA) and influences GDF5 allelic expression in vitro and... LA - eng KW - Greece KW - Aged KW - Female KW - Humans KW - Male KW - Middle Aged KW - Spain KW - Aged, 80 and over KW - Case-Control Studies KW - Cohort Studies KW - Polymorphism, Single Nucleotide KW - United Kingdom KW - High-Throughput Nucleotide Sequencing KW - Osteoarthritis KW - Genetic Predisposition to Disease KW - Sequence Analysis, DNA KW - Growth Differentiation Factor 5 TI - Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus DO - 10.1016/j.joca.2011.01.014 T2 - Osteoarthritis And Cartilage M2 - 430 VL - 19 ER -