TY - JOUR AU - Ramos Amigo, Adriana AU - Rodríguez-Seoane, C. AU - Rosa Benito, Isaac AU - Trossbach, S. V. AU - Ortega-Alonso, A. AU - Tomppo, L. AU - Ekelund, J. AU - Veijola, J. AU - Järvelin, M. R. AU - Alonso Lorenzo, Jana AU - Veiga García, Sonia AU - Sawa, A. AU - Hennah, W. AU - García Alonso, Ángel AU - Korth, C. AU - Rodríguez Requena, Jesús PY - 2014 SN - 0964-6906 UR - http://hdl.handle.net/20.500.11940/5977 AB - In a large Scottish pedigree, disruption of the gene coding for DISC1 clearly segregates with major depression, schizophrenia and related mental conditions. Thus, study of DISC1 may provide a clue to understand the biology of major mental illness. A... LA - eng KW - Anhedonia KW - Brain KW - Cohort Studies KW - Down-Regulation KW - Humans KW - Mental Disorders KW - Nerve Growth Factors KW - Nerve Tissue Proteins KW - Neurons KW - Pedigree KW - Polymorphism, Single Nucleotide TI - Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1 DO - 10.1093/hmg/ddu303 T2 - HUMAN MOLECULAR GENETICS M2 - 5859 VL - 23 ER -