TY  - JOUR 
AU  - Leiro Fernández, Virginia
AU  - Valverde, D.
AU  - Vázquez Gallardo, Eladio Rafael
AU  - Botana Rial, María Isabel
AU  - Constenla Caramés, Lucia
AU  - Agundez, J. A.
AU  - Fernández Villar, José Alberto
PY  - 2011
SN  - 1027-3719
UR  - http://hdl.handle.net/20.500.11940/6566
AB  - OBJECTIVE: To analyse slow-acetylation N-acetyltransferase 2 (NAT2) polymorphisms for their association with the risk of anti-tuberculosis drug-induced hepatotoxicity (ATDH). DESIGN: A case-control study including Caucasian patients with tuberculosis...
LA  - eng
KW  - Adult
KW  - Antitubercular Agents
KW  - Arylamine N-Acetyltransferase
KW  - Case-Control Studies
KW  - Chemical and Drug Induced Liver Injury
KW  - Chi-Square Distribution
KW  - European Continental Ancestry Group
KW  - Female
KW  - Gene Frequency
KW  - Genetic Predisposition to Disease
KW  - Haplotypes
KW  - Humans
KW  - Isoniazid
KW  - Logistic Models
KW  - Male
KW  - Middle Aged
KW  - Odds Ratio
KW  - Phenotype
KW  - Polymorphism, Genetic
KW  - Pyrazinamide
KW  - Rifampin
KW  - Risk Assessment
KW  - Risk Factors
KW  - Tuberculosis
TI  - N-acetyltransferase 2 polymorphisms and risk of anti-tuberculosis drug-induced hepatotoxicity in Caucasians
DO  - 10.5588/ijtld.10.0648
T2  - INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
VL  - 15
ER  -