TY - JOUR AU - Cruz-Herrera, C.F. AU - Campagna M AU - Lang V AU - del Carmen González-Santamaría, J AU - Marcos-Villar, L AU - Rodríguez, MS AU - Vidal Figueroa, Anxo AU - Collado Rodríguez, Manuel AU - Rivas, C PY - 2015 SN - 0950-9232 UR - http://hdl.handle.net/20.500.11940/8180 AB - Serine threonine kinase AKT has a central role in the cell, controlling survival, proliferation, metabolism and angiogenesis. Deregulation of its activity underlies a wide range of pathological situations, including cancer. Here we show that AKT is... LA - eng KW - 3T3 Cells KW - Animals KW - Apoptosis KW - COS Cells KW - Cell Line, Tumor KW - Cell Proliferation KW - Chlorocebus aethiops KW - Enzyme Activation KW - Female KW - HEK293 Cells KW - HeLa Cells KW - Humans KW - MCF-7 Cells KW - Mice KW - Mutation KW - Neoplasms KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphorylation KW - Proto-Oncogene Proteins c-akt KW - SUMO-1 Protein KW - Small Ubiquitin-Related Modifier Proteism KW - Sumoylatigy KW - Ubiquitism TI - SUMOylation regulates AKT1 activity DO - 10.1038/onc.2014.48 T2 - ONCOGENE M2 - 1442 VL - 34 ER -