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dc.contributor.authorViñolas, N Nuria
dc.contributor.authorGarcía Campelo, María del Rosario 
dc.contributor.authorMajem, Margarita
dc.contributor.authorCarcereny, Enric
dc.contributor.authorIsla, Dolores
dc.contributor.authorGonzalez-Larriba, José Luis
dc.contributor.authorCoves, Juan
dc.contributor.authorDe-Castro, Javier
dc.contributor.authorDomine, Manuel
dc.contributor.authorLianes, Piar
dc.contributor.authorArtal, Angel
dc.contributor.authorRemon, Jordi
dc.contributor.authorFelip, Enriqueta
dc.contributor.authorGarrido, Pilar
dc.date.accessioned2022-03-08T08:49:07Z
dc.date.available2022-03-08T08:49:07Z
dc.date.issued2020
dc.identifier.issn2050-7283
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/33228796es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/16190
dc.description.abstractBACKGROUND: Little is known about the impact of sex on lung cancer patients from the psychological, economic and social perspectives. This study was designed to explore the psychosocial and economic impact according to sex of metastatic non-small cell lung cancer (mNSCLC) in patients and caregivers. METHODS: Exploratory study of two cohorts of patients starting first-line treatment for mNSCLC. The following questionnaires were administered at baseline, 4 months later and following the first and second disease progression: APGAR, relationship impact scale, DUKE-UNC scale, economic impact in patients and caregiver, and Zarit scale. It was planned to include 1250 patients to get an 80% possibility of detecting as significant (p < 0.05) effect sizes less than 0.19 between men and women. Univariate comparisons were made between the tests applied to men and women. Overall survival was estimated with Kaplan-Meier method. Cox analyses were done to estimate hazard ratios (HRs) with 95% CI. RESULTS: 333 patients were included. Most families reported to continue being functional despite the lung cancer diagnosis. Regardless of sex, they did not perceive changes in their partner relationship. Most patients felt their social support was normal. Roughly 25% of people reported a worsening in their economic situation, without remarkable differences by sex. Statistically significant differences were found between both groups regarding the caregiver's relationship to the patient (more parents were the caregiver in females than in males, p < 0.0001) and the caregiver's employment situation (more employed caregivers in females) (p < 0.0001). Most caregivers of both sexes considered that taking care of their relative did not pose a significant burden. CONCLUSIONS: This study provides a preliminary insight into sex-related characteristics in the management of advanced NSCLC and its impact on the emotional, social and economic burden of patients and their caregivers, and recall the high priority of researching in cancer from a sex perspective. Nevertheless, due to the low recruitment rate and the relevant loss of patients during the follow-up, it was difficult to find differences by sex. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT02336061. ETHICS COMMITTEE: Comite Etico de Investigacion Clinica del Hospital Clinic de Barcelona, Spain. Reference number: HCB/2014/0705.en
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.meshLung Neoplasms*
dc.subject.meshLongitudinal Studies*
dc.subject.meshCarcinoma*
dc.subject.meshMiddle Aged*
dc.subject.meshHumans*
dc.subject.meshSocial Support*
dc.subject.meshProspective Studies*
dc.subject.meshSocioeconomic Factors*
dc.subject.meshSex Characteristics*
dc.subject.meshAged*
dc.titleAssessment of the psychosocial and economic impact according to sex in non-small cell lung cancer patients: an exploratory longitudinal studyen
dc.typeJournal Articlees
dc.authorsophosViñolas, N Nuria;Garcia-Campelo, Rosario;Majem, Margarita;Carcereny, Enric;Isla, Dolores;Gonzalez-Larriba, José Luis;Coves, Juan;De-Castro, Javier;Domine, Manuel;Lianes, Piar;Artal, Angel;Remon, Jordi;Felip, Enriqueta;Garrido, Pilar
dc.identifier.doi10.1186/s40359-020-00489-z
dc.identifier.pmid33228796
dc.identifier.sophos35763
dc.issue.number1es
dc.journal.titleBMC Psychologyes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de A Coruña - Complexo Hospitalario Universitario de A Coruña::Oncoloxía médicaes
dc.relation.publisherversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685640/pdf/40359://2020://Article://489.pdfes
dc.rights.accessRightsopenAccess
dc.subject.decsapoyo social*
dc.subject.decscarcinoma*
dc.subject.decsanciano*
dc.subject.decsestudios longitudinales*
dc.subject.decsestudios prospectivos*
dc.subject.decsmediana edad*
dc.subject.decshumanos*
dc.subject.decsfactores socioeconómicos*
dc.subject.decsneoplasias pulmonares*
dc.subject.decscaracterísticas sexuales*
dc.subject.keywordCHUACes
dc.typefidesArtículo Originales
dc.typesophosArtículo Originales
dc.volume.number8es


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Atribución 4.0 Internacional
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