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Action Mechanisms of Small Extracellular Vesicles in Inflammaging

dc.contributor.authorMato Basalo, Rocío
dc.contributor.authorLucio-Gallego, S.
dc.contributor.authorAlarcón-Veleiro, C.
dc.contributor.authorSacristán-Santos, M.
dc.contributor.authorQuintana, M.P.M.
dc.contributor.authorMorente López, Miriam
dc.contributor.authorDe Toro Santos, Francisco Javier 
dc.contributor.authorSilva Fernández, Lucía 
dc.contributor.authorGonzález-Rodríguez, A.
dc.contributor.authorArufe Gonda, Mª del Carmen
dc.contributor.authorFafian Labora, Juan
dc.date.accessioned2025-08-25T12:44:18Z
dc.date.available2025-08-25T12:44:18Z
dc.date.issued2022
dc.identifier.citationMato-Basalo R, Lucio-Gallego S, Alarcón-Veleiro C, Sacristán-Santos M, Quintana MDPM, Morente-López M, et al. Action Mechanisms of Small Extracellular Vesicles in Inflammaging. Life. MDPI; 2022;12(4).
dc.identifier.issn2075-1729
dc.identifier.otherhttps://portalcientifico.sergas.gal/documentos/626d90bd3541a83b39a1cd2a*
dc.identifier.urihttp://hdl.handle.net/20.500.11940/20530
dc.description.abstractThe accumulation process of proinflammatory components in the body due to aging influences intercellular communication and is known as inflammaging. This biological mechanism relates the development of inflammation to the aging process. Recently, it has been reported that small extracellular vesicles (sEVs) are mediators in the transmission of paracrine senescence involved in inflammatory aging. For this reason, their components, as well as mechanisms of action of sEVs, are relevant to develop a new therapy called senodrugs (senolytics and senomorphic) that regulates the intercellular communication of inflammaging. In this review, we include the most recent and relevant studies on the role of sEVs in the inflammatory aging process and in age-related diseases such as cancer and type 2 diabetes.en
dc.description.sponsorshipJ.F.L. was funded by Xunta de Galicia, Grant Number ED481D-2021-020. M.C.A. received a grant from the Spanish National Health Institute Carlos III (PI20/00497).en
dc.language.isoeng
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleAction Mechanisms of Small Extracellular Vesicles in Inflammaging*
dc.typeReviewen
dc.authorsophosMato-Basalo, J. A. F. R.
dc.authorsophosLucio-Gallego, S.
dc.authorsophosAlarcón-Veleiro, C.
dc.authorsophosSacristán-Santos, M.
dc.authorsophosQuintana, M. P. M.
dc.authorsophosMorente-López, M.
dc.authorsophosde Toro, F. J.
dc.authorsophosSilva-Fernández, L.
dc.authorsophosGonzález-Rodríguez, A.
dc.authorsophosArufe, M. C.
dc.authorsophosLabora
dc.identifier.doi10.3390/life12040546
dc.identifier.sophos626d90bd3541a83b39a1cd2a
dc.issue.number4
dc.journal.titleLife*
dc.page.initialnull
dc.relation.projectIDXunta de Galicia [ED481D-2021-020]; Spanish National Health Institute Carlos III [PI20/00497]
dc.relation.publisherversionhttps://www.mdpi.com/2075-1729/12/4/546/pdf?version=1649253564;https://mdpi-res.com/d_attachment/life/life-12-00546/article_deploy/life-12-00546.pdf?version=1649253564es
dc.rights.accessRightsopenAccess
dc.subject.keywordINIBICes
dc.subject.keywordAS Coruñaes
dc.subject.keywordCHUACes
dc.typefidesArtículo Científico (incluye Original, Original breve, Revisión Sistemática y Meta-análisis)es
dc.typesophosArtículo de Revisiónes
dc.volume.number12


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