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Anagrelide treatment in early pregnancy in a patient with JAK2V617F-positive essential thrombocythemia: case report and literature review

dc.contributor.authorSobas, Marta Anna
dc.contributor.authorPérez Encinas, Manuel Mateo 
dc.contributor.authorRabuñal Martínez, María
dc.contributor.authorQuinteiro García, Celsa 
dc.contributor.authorBello López, José Luis 
dc.date.accessioned2026-02-13T11:18:43Z
dc.date.available2026-02-13T11:18:43Z
dc.date.issued2009
dc.identifier.otherhttps://pubmed.ncbi.nlm.nih.gov/19887779/es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/22721
dc.description.abstract[EN] Essential thrombocythemia (ET) has 2 peaks of incidence: one is at 60 years of age, the other at 30 years. In women, the peak at the earlier age presents challenges for management in Nevertheless, HDU and ANA are not recommended during pregnancy because of embryo/ fetotoxic effects observed in animals . There are scarce clinical data on adverse incidents when ANA is used during pregnancy in humans. We present a successful outcome of a 32-year-old woman with ET who was treated with ANA before becoming pregnant and during early pregnancy.es
dc.language.isoenges
dc.subject.meshPregnancy *
dc.subject.meshQuinazolines *
dc.subject.meshInfant, Newborn *
dc.subject.meshThrombocythemia, Essential *
dc.subject.meshFemale *
dc.subject.meshPregnancy Complications, Hematologic *
dc.subject.meshWomen *
dc.subject.meshPregnancy Outcome *
dc.titleAnagrelide treatment in early pregnancy in a patient with JAK2V617F-positive essential thrombocythemia: case report and literature reviewes
dc.typeArtigoes
dc.identifier.doi10.1159/000253030
dc.identifier.essn1421-9662
dc.identifier.pmid19887779
dc.issue.number4es
dc.journal.titleActa Haematologicaes
dc.organizationServizo Galego de Saúde::Áreas Sanitarias (A.S.)::Área Sanitaria de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Hematoloxía clínicaes
dc.page.initial221es
dc.page.final222es
dc.relation.publisherversionhttps://karger.com/aha/article-abstract/122/4/221/14905/Anagrelide-Treatment-in-Early-Pregnancy-in-aes
dc.rights.accessRightsembargoedAccesses
dc.subject.cie10Trombocitemia idiopática (D47.3) es
dc.subject.decsresultado del embarazo *
dc.subject.decscomplicaciones hematológicas del embarazo *
dc.subject.decsembarazo *
dc.subject.decsquinazolinas *
dc.subject.decstrombocitemia esencial *
dc.subject.decsrecién nacido *
dc.subject.keywordCHUSes
dc.typefidesNota Clínica (inclue Casos Clínico)es
dc.typesophosArtículo Originales
dc.volume.number122es


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