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Genomic characterisation of respiratory syncytial virus: a novel system for whole genome sequencing and full-length G and F gene sequences

dc.contributor.authorIglesias-Caballero, M.*
dc.contributor.authorCamarero-Serrano, S.*
dc.contributor.authorVarona, S.*
dc.contributor.authorMas, V.*
dc.contributor.authorCalvo, C.*
dc.contributor.authorGarcía, M.L.*
dc.contributor.authorGarcía Costa, Juan *
dc.contributor.authorVázquez-Morón, S.*
dc.contributor.authorMonzón, S.*
dc.contributor.authorCampoy, A.*
dc.contributor.authorCuesta, I.*
dc.contributor.authorPozo, F.*
dc.contributor.authorCasas, I.*
dc.date.accessioned2025-09-09T11:25:44Z
dc.date.available2025-09-09T11:25:44Z
dc.date.issued2023
dc.identifier.citationIglesias-Caballero M, Camarero-Serrano S, Varona S, Mas V, Calvo C, García ML, et al. Genomic characterisation of respiratory syncytial virus: a novel system for whole genome sequencing and full-length G and F gene sequences. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 2023;28(49).
dc.identifier.issn1560-7917
dc.identifier.otherhttps://portalcientifico.sergas.gal//documentos/65911dbbae63c86e421b9c34
dc.identifier.urihttp://hdl.handle.net/20.500.11940/21536
dc.description.abstractTo advance our understanding of respiratory syncytial virus (RSV) impact through genomic surveillance, we describe two PCR-based sequencing systems, (i) RSVAB-WGS for generic whole-genome sequencing and (ii) RSVAB-GF, which targets major viral antigens, G and F, and is used as a complement for challenging cases with low viral load. These methods monitor RSV genetic diversity to inform molecular epidemiology, vaccine effectiveness and treatment strategies, contributing also to the standardisation of surveillance in a new era of vaccines.
dc.description.sponsorshipThis research was partially funded by Instituto de Salud Carlos III through the Project PI18/00167, PI21CIII/00019 (MPY 439-21) and PI21/00377, and partially by UNESPA donation-COVIDSEQUNESPA (grant number MPY 226/22) . Also, funding was received from grant MSD MISP: IISP 60255.
dc.languageeng
dc.rightsAttribution 4.0 International (CC BY 4.0)*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshHumans *
dc.subject.meshRespiratory Syncytial Virus Infections *
dc.subject.meshViral Fusion Proteins *
dc.subject.meshRespiratory Syncytial Virus Vaccines *
dc.subject.meshRespiratory Syncytial Virus, Human*
dc.subject.meshGenomics *
dc.subject.meshWhole Genome Sequencing *
dc.subject.meshAntibodies, Viral *
dc.titleGenomic characterisation of respiratory syncytial virus: a novel system for whole genome sequencing and full-length G and F gene sequences
dc.typeArtigo
dc.authorsophosIglesias-Caballero, M.; Camarero-Serrano, S.; Varona, S.; Mas, V.; Calvo, C.; García, M.L.; García-Costa, J.; Vázquez-Morón, S.; Monzón, S.; Campoy, A.; Cuesta, I.; Pozo, F.; Casas, I.
dc.identifier.doi10.2807/1560-7917.es.2023.28.49.2300637
dc.identifier.sophos65911dbbae63c86e421b9c34
dc.issue.number49
dc.journal.titleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin*
dc.organizationServizo Galego de Saúde::Áreas Sanitarias (A.S.) - Complexo Hospitalario Universitario de Ourense::Microbioloxía
dc.relation.projectIDInstituto de Salud Carlos III [PI18/00167, PI21CIII/00019 (MPY 439-21), PI21/00377]
dc.relation.projectIDUNESPA donation-COVIDSEQUNESPA [MPY 226/22]
dc.relation.projectIDMSD [MISP: IISP 60255]
dc.relation.publisherversionhttps://doi.org/10.2807/1560-7917.es.2023.28.49.2300637
dc.rights.accessRightsopenAccess*
dc.subject.keywordAS Ourense
dc.subject.keywordCHUO
dc.typefidesArtículo Científico (incluye Original, Original breve, Revisión Sistemática y Meta-análisis)
dc.typesophosArtículo Original
dc.volume.number28


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